Utilization of Secondary Metabolites in Algae Kappaphycus alvarezii as a Breast Cancer Drug with a Computational Method
نویسندگان
چکیده
Breast cancer is one of the worst diseases that affect female people. Long-term treatment with therapy or surgery has a detrimental impact on patient. The algae Kappaphycus alvarezii gotten lot interest as breast medication because it contains chemicals are expected to be anti-cancer. objectives this paper were see how secondary metabolites in interact Nuclear Factor- kappaB protein kinase cancer. ligands and proteins obtained from PubChem PDB websites, respectively. Swiss ADME was then used assess Pharmacokinetics Drug likeness Properties. last stage involved using molecular docking PyRx dynamics identify interaction visualization between ligand target protein. findings test revealed maraniol chemical had superior binding capacity NF kB chromone group controls transport efficiently preventing proliferation.
منابع مشابه
Analysis of Bioactive Compounds and Antimicrobial Activity of Marine Algae Kappaphycus Alvarezii Using Three Solvent Extracts
The seaweeds are economically valuable resources, used as food, fodder, fertilizer and medicine and thus useful to mankind in many ways. In the present study, Kappaphycus alvarezii, a marine alga, has been analysed for the presence of bioactive products using three solvent extracts. Antimicrobial activity was also done using the same extracts of seaweed. The results revealed that the selected s...
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ژورنال
عنوان ژورنال: Pharmacognosy Journal
سال: 2022
ISSN: ['0975-3575']
DOI: https://doi.org/10.5530/pj.2022.14.68